Macuna Pruriens Extract

Introduction of Macuna Pruriens Extract：

Mucuna Pruriens is a tropical legume plant native to Africa, India, and the Caribbean. It is also commonly known as Velvet Bean, Cowhage, or Cowitch. The plant is famous for its pods, which are covered in tiny, silky hairs that cause intense itching if they come into contact with skin.

However, the seeds of this plant are a nutritional and medicinal powerhouse. Mucuna Pruriens Extract is a concentrated form derived from these seeds, standardized for its most notable active compound: L-Dopa (Levodopa).

• Key Active Compound: L-Dopa is the direct precursor to the neurotransmitter dopamine. Dopamine is crucial for regulating mood, motivation, sleep, and movement. The human body uses L-Dopa to synthesize dopamine in the brain.

• Traditional Use: In Ayurvedic medicine (where it is known as Kapikachhu), Mucuna has been used for centuries as a nerve tonic, aphrodisiac, and remedy for nervous system disorders like Parkinson’s disease.

• The Extract: Modern supplements use extracts standardized to contain a specific percentage of L-Dopa (typically 15%-99%), ensuring consistent potency and effectiveness.

Benefit of Macuna Pruriens Extract:

The benefits are primarily linked to its L-Dopa content and its subsequent effect on dopamine levels.

1. Natural Support for Parkinson’s Disease

• How it works: This is the most well-researched benefit. Parkinson’s disease is characterized by low dopamine levels in the brain. The L-Dopa in Mucuna Pruriens crosses the blood-brain barrier and is converted into dopamine, helping to alleviate motor symptoms.

• Benefit: Studies have shown it can be as effective as conventional synthetic L-Dopa medication in reducing symptoms like tremors, stiffness, and impaired movement, often with a smoother onset and fewer side effects like dyskinesia (involuntary movements).

2. Enhances Mood and Fights Depression

• How it works: By boosting dopamine levels, Mucuna Pruriens can improve mood, motivation, and a sense of well-being. Dopamine is a key “reward” and “pleasure” chemical in the brain.

• Benefit: May help reduce symptoms of depression, anxiety, and stress. Users often report improved outlook, increased drive, and enhanced enjoyment of activities.

3. Boosts Libido and Reproductive Health

• How it works: Dopamine plays a significant role in libido and sexual function. Furthermore, Mucuna Pruriens has been shown to:

  • Increase testosterone levels: By potentially influencing the hypothalamic-pituitary-gonadal axis.

  • Improve sperm parameters: Studies indicate it can significantly increase sperm count, motility, and volume in men with infertility issues.

  • Reduce stress hormones: High cortisol (stress hormone) can suppress testosterone and libido; Mucuna helps modulate the stress response.

• Benefit: A powerful natural aphrodisiac for both men and women. It is particularly beneficial for improving male fertility and addressing low testosterone symptoms.

4. Improves Growth Hormone Levels and Athletic Performance

• How it works: Intense exercise is a potent stimulator of Growth Hormone (GH) release. L-Dopa/dopamine can further enhance this natural pulse of GH. GH is essential for muscle growth, fat metabolism, and recovery.

• Benefit: Athletes and bodybuilders use it to support muscle growth, increase strength, enhance endurance, and improve recovery times between workouts.

5. Powerful Antioxidant and Neuroprotective Effects

• How it works: The seeds contain various antioxidants that help protect cells from damage caused by free radicals. This is particularly important for protecting dopamine-producing neurons in the brain from oxidative stress.

• Benefit: Supports long-term brain health, may slow the aging process of neurons, and contributes to the overall neuroprotective effect seen in its use for Parkinson’s.

6. Adaptogenic and Stress-Relieving Properties

• How it works: As an adaptogen, it helps the body adapt to and resist physical and mental stress. By modulating cortisol and boosting dopamine, it promotes a state of calm focus and resilience.

• Benefit: Helps combat the effects of chronic stress, improves sleep quality, and supports cognitive function under pressure.

Summary of Benefits Table

Dosage and Important Safety Considerations

• Dosage: Dosage depends heavily on the L-Dopa standardization.

  • A common dose for general mood and libido support is an extract standardized to 15% L-Dopa, taken at 300-600 mg per day.

  • For therapeutic uses like Parkinson’s support, higher doses (e.g., 30-50% L-Dopa extract) under medical supervision are common.

  • Always follow the product’s specific dosage instructions.

• Safety and Side Effects:

  • Consult a Doctor: Crucially, if you have Parkinson’s disease and are on medication, do not self-prescribe. Combining it with synthetic L-Dopa (Sinemet) can lead to a dangerous overdose of dopamine, causing severe side effects. Medical supervision is essential.

  • Potential Side Effects: At high doses, it may cause nausea, vomiting, or dizziness due to the rapid increase in dopamine.

  • Pregnancy/Breastfeeding: Not recommended due to a lack of safety data.

  • Quality Matters: Source from reputable suppliers to ensure the product is free from contaminants and accurately labeled for L-Dopa content.

Packing of Macuna Pruriens Extract:

25kg/ドラム、紙ドラムと二重のビニール袋で梱包。

Storage of Macuna Pruriens Extract:

湿気、光、酸素を避けて、密閉容器で保管すること。

Shelf life of Macuna Pruriens Extract:

上記の条件下で、オリジナルのパッケージで24ヶ月間。